Illumina MiSeq system with the Burrows-Wheeler Aligner MEM algorithm
The Illumina MiSeq system is a high-throughput sequencing platform that is used for DNA and RNA sequencing. It uses a technology called Next-Generation Sequencing (NGS) to generate large amounts of sequence data.
The Burrows-Wheeler Aligner (BWA) MEM algorithm is a popular software tool used to align sequencing reads to a reference genome. It is used to map the short sequencing reads generated by NGS platforms like the Illumina MiSeq to a reference genome, allowing for the identification of genetic variants and mutations. The BWA-MEM algorithm is highly accurate and efficient, making it a popular choice for genome analysis.
In combination, the Illumina MiSeq system and the BWA-MEM algorithm provide a powerful tool for genetic research and the study of diseases like Covid-19. They can be used to sequence the viral genome and identify genetic mutations, which can inform the development of diagnostic tests and treatments.
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